A different kind
of insulin pump

Meet twiist™, an effective and more personalized Automated Insulin Delivery (AID) System for people with type 1 diabetes.1-6

Meet twiist™, an effective and more personalized Automated Insulin Delivery (AID) System for people with type 1 diabetes.1-6

Learn what’s possible with twiist

I’m interested!

Innovative technology designed to adapt to your day.

Detects blockages up to 9x faster than other pumps*

Customizable glucose target range, anywhere from 87 to 180 mg/dL

Smallest pump that holds 300 units1-6

Smartphone and smartwatch compatibility

Adaptable

Unique features let you customize it to your day in ways other pumps can’t.1-6

  • Adjustable glucose targets before meals and activity
  • Change a carb entry or the time you ate, even after eating
  • Flexible wear options that you can change as needed
Adhesive options for on-body wear are currently being developed.
Certain

Advanced technology precisely measures the actual volume of insulin delivered.

  • Detects blockages faster than other pumps,* in about 19 minutes (at a basal rate of 1 U/hr), so you can potentially take action before you go high7
  • The only pump that measures the actual volume of insulin delivered at every dose
  • Powered by iiSure™ sound wave technology for accuracy and predictability
Adhesive options for on-body wear are currently being developed.
Effective

Helps prevent highs and lows, day and night, with our intelligent software.

  • Loop is the basis of twiist Loop, the tech powering twiist
  • Automatically adjusts basal insulin to help reduce highs and lows
  • Up to a 90% drop in severe lows seen in an analysis of the Loop Observational Study8†
“
If I could describe twiist in one word, it would be ‘magical.’ It feels like beyond my wildest dreams that I could feel so relaxed and so at ease just from a little machine.”
Brooke
twiister with type 1 diabetes
“
The thing that I love most about twiist is how it reduces the mental load of living with diabetes for me. It is such a relief to be able to live life and not feel captive to my diabetes.”
Cheyne
twiister with type 1 diabetes
“
I love twiist for what it represents, a shift in diabetes care that gives me options.”
Arnie
twiister with type 1 diabetes

Caring for someone with type 1 diabetes?

With the twiist insiight™ App, monitor your loved one's data from anywhere,
with visibility into glucose and pump status, including notifications for key events.‡

Learn more

Getting started with your twiist AID System is easy

1.

Let your doctor know you’re interested in the twiist AID System

2.

You may be able to get twiist for $0 the first month, and no more than $50/month thereafter§

Complete this form or give us a call at 1-877-4twiist (1-877-489-4478) Monday–Friday, 9 AM to 9 PM EST for guidance regarding your coverage. Or text HELLO to twiist (894478) for more info.

3.

Get your prescription twiist Starter Kit from the pharmacy

4.

Scan the QR code included in the Starter Kit to arrange your live training and begin your journey with the twiist AID System

Take a closer look at all there is to love about twiist!

Awards & Features

The twiist AID System is the winner of the 2026 MedTech Breakthrough Award

Best New Technology Solution for Diabetes Management

Press release

"MedTech Breakthrough" and the MedTech Breakthrough logo are licensed trademarks of MedTech Breakthrough.

*
Calculation based on a comparison of the following IFUs. The following reported 1 U/hr basal rate: Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide; Insulet - Omnipod 5 Automated Insulin Delivery System User Guide; Medtronic - MiniMed 780G system User Guide; Beta Bionics - iLet Bionic Pancreas System User Guide. The following reported 2 U/hr basal rate: Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide; Tandem Diabetes Care - Tandem Mobi System User Guide.
†
Results obtained with the Loop algorithm using a non-twiist device.
‡
The insiight App is not intended to be a replacement for the information displayed by the twiist System App and should not inform dosing decisions. It is not intended to replace self-monitoring practices as advised by a physician. Data updates require WiFi or cellular connectivity and their frequency may vary depending on connection strength.
§
The twiist™ Savings Program is available to individuals with a valid prescription and commercial insurance that covers twiist. Eligible participants can receive a Starter Kit for $0 and pay no more than $50 for Refill Kits. This offer is not valid for individuals enrolled in Medicare, Medicaid, or any other federal or state programs, or for cash-paying patients and non-covered claims. It is available only in the U.S. and is not valid in Puerto Rico, U.S. Territories, or where prohibited by law. While most commercially insured participants qualify for the $50 Refill Kit offer, those with high-deductible plans who haven't met their deductible may pay more than $50 per Refill Kit until their deductible is met. The maximum benefit is $200 per Refill Kit for covered claims. Terms are subject to change. Call us at 1-877-489-4478 or contact your insurance provider to confirm coverage.  
REFERENCES
  1. Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide.
  2. lnsulet - Omnipod 5 Automated Insulin Delivery System User Guide.
  3. Medtronic - MiniMed 780G system User Guide.
  4. Beta Bionics - iLet Bionic Pancreas System User Guide.
  5. Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide.
  6. Tandem Diabetes Care - Tandem Mobi System User Guide.
  7. Klonoff DC, et al. Time to Moderate and Severe Hyperglycemia and Ketonemia Following an Insulin Pump Occlusion. J Diabetes Sci Technol. 2024;18(6):1472-1479.
  8. Lum JW, et al. A Real-World Prospective Study of the Safety and Effectiveness of the Loop Open Source Automated Insulin Delivery System. Diabetes Technol Ther. 2021;23(5):367-375.
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