Auto Adjust by twiist Loop has you covered
The twiist AID System updates predictions every 5 minutes to create a 6-hour glucose forecast.
Not just an insulin pump
A breakthrough in diabetes management. That’s the twiist™.
Adhesive options for on-body wear are currently being developed.
It looks and works like
no other pump around
The twiist Automated Insulin Delivery (AID) System puts you in control of how you manage your diabetes. Unique features let you personalize how you use it. Innovative technology ensures dosing accuracy. And you get it all without multiple daily injections (MDI).
The twiist AID System is the twiist Pump, your continuous glucose monitor (CGM), and the Loop technology that powers twiist.
What makes twiist so unique?
Customizable glucose target(s)
You can set your target anywhere between 87-180 mg/dL, the widest correction range of any available AID system, so you can stay in the range that is right for you.1-6
Pre-meal and activity presets
The only AID system where you can adjust your glucose targets before both meals AND exercise.
twiist Loop glucose forecast
twiist updates your 6-hour glucose prediction every 5 minutes based on CGM readings, your personalized settings, and predicted glucose levels. Loop adjusts basal insulin all day and night to help prevent highs and lows.
iiSure™ Technology
Ensures precise insulin delivery down to the microdose and detects blockages up to 9x faster than any other AID system, in about 19 minutes, potentially reducing unexpected highs.7,8*
Small but mighty
The twiist Pump weighs less than 2oz, and holds 300 units, making it the smallest available pump with such a large capacity.1-6
Smartphone and smartwatch integration
Connect your smartphone or smartwatch for convenient, app-based control. The twiist AID System is the only AID system that can be controlled from a smartwatch.1-6
Flexible wear options
Put it in your pocket. Clip it on your hip. Or stick it to your body. Wear twiist how you want.
Personalized mealtime
Mealtime plans changed? Only twiist lets you change a carb entry or the time you ate AFTER a meal.1-6 You can also specify whether the food you eat contains fast-, medium-, or slow-absorbing carbs, and twiist will take this into account when delivering mealtime insulin doses.
With twiist, you can
control insulin delivery
3 ways
1.
Compatible smartphone
2.
Compatible smartwatch
3.
On-pump bolus button
Check out our current compatible CGMs
More CGM sensor compatibility options are on the way!
The world's smallest 15-day CGM sensor delivers glucose readings every minute.9
The first and only one-year CGM,
providing 365 days of uninterrupted glucose readings.10-12*
Recalculates
These predictions are calculated using your CGM readings, personalized settings, insulin delivery history, and carb history.
Adjusts
Based on these predictions, twiist automatically adjusts basal insulin delivery every 5 minutes, so glucose will ultimately meet your personal correction target.
Helps prevent highs and lows
twiist automatically adjusts your basal insulin delivery in an effort to reach your target glucose and help prevent highs and lows.
Caring for someone with diabetes?
Stay connected from anywhere. The twiist insiight™ App lets you remotely view their glucose, insulin, and carb info from your compatible smartphone or smartwatch.‡ It’s also the only app that can notify caregivers to insulin blockages remotely.§
Your child’s away at school or camp? Your spouse is on a business trip? No matter where they are, you have peace of mind.
Learn what’s possible with twiist
I have type 1 diabetes
Discover twiistI have type 2 diabetes
Discover twiist*
Calculation based on a comparison of the following IFUs. The following reported 1 U/hr basal rate: Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide; lnsulet - Omnipod 5 Automated Insulin Delivery System User Guide; Medtronic - MiniMed 780G system User Guide; Beta Bionics - iLet Bionic Pancreas System User Guide. The following reported 2 U/hr basal rate: Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide; Tandem Diabetes Care - Tandem Mobi System User Guide.
†
The Eversense 365 Continuous Glucose Monitoring (CGM) System is indicated for continually measuring glucose levels for up to one year in people (18 years and older) with diabetes. For important safety information, see
bit.ly/eversensesafety.
‡
The insiight App is not intended to be a replacement for the information displayed by the twiist System App and should not inform dosing decisions. It is not intended to replace self-monitoring practices as advised by a physician. Data updates require WiFi or cellular connectivity and their frequency may vary depending on connection strength.
§
When comparing labelling of commercially available Caregiver Apps in the United States as of April 2026.
REFERENCES
- Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide.
- lnsulet - Omnipod 5 Automated Insulin Delivery System User Guide.
- Medtronic - MiniMed 780G system User Guide.
- Beta Bionics - iLet Bionic Pancreas System User Guide.
- Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide.
- Tandem Diabetes Care - Tandem Mobi System User Guide.
- Klonoff DC, et al. Time to Moderate and Severe Hyperglycemia and Ketonemia Following an Insulin Pump Occlusion. J Diabetes Sci Technol. 2024;18(6):1472-1479.
- Kudva YC, Raghinaru D, Lum JW, et al. A randomized trial of automated insulin delivery in type 2 diabetes. N Engl J Med. 2025;392(18):1801-1812.
- FreeStyle Libre 3 System. FreeStyle Libre US. Accessed September 23, 2026. https://www.freestyle.abbott/us-en/products/freestyle-libre-3.html
- Eversense® 365 User Guide.
- FreeStyle Libre 3 User Guide.
- Dexcom G7 User Guide.
MAT-0426 V4.0 09/26
