The tech that powers twiist™
Get to know the technology that's seamlessly integrated into the twiist Automated Insulin Delivery (AID) System.


The twiist AID System is the first automated insulin delivery system powered by Tidepool
twiist Loop is based on Tidepool Loop, an intuitive, smart technology that was originally designed by people with diabetes and their caregivers for people with diabetes!


Dynamic adjustments
Basal delivery
Every 5 minutes, twiist calculates your 6-hour glucose forecast based on your active insulin, active carb data, CGM readings, and therapy settings, and adjusts basal insulin to help keep you in your personalized target glucose range.
It's like a GPS. twiist sees where your glucose is headed and makes adjustments to keep you going in the right direction.
Bolus recommendations
twiist recommends mealtime insulin doses based on the number of carbs and absorption rates you enter.


How is twiist different from multiple daily injections (MDI)?
With twiist, you can say goodbye to daily injections. twiist delivers your basal insulin doses automatically.
twiist connects with your continuous glucose monitor (CGM) and calculates how much basal insulin you need throughout the day and night, to help prevent your glucose from going too high or low. It also calculates mealtime insulin doses based on your carbs and how quickly they absorb.
This takes the pressure off you to always have to calculate exactly how much insulin you need.
Redefining diabetes management
In an analysis of the Loop Observational Study, the Loop technology demonstrated clinically meaningful improvements among people living with T1D in glucose control and other quality-of-life measurements.1,2*
Improvement in time in range1
Loop users spent more time within target glucose levels, helping reduce the risk of long-term complications.
Reduction in severe hypoglycemia1
Dramatically decreasing the occurrence of dangerous low blood sugar episodes.
Decrease in diabetes distress2
Alleviating the emotional and mental burden associated with diabetes management.
Improvement in sleep quality2
Promoting better rest and overall well-being for people with diabetes.
Learn what’s possible with twiist
I have type 1 diabetes
Discover twiistI have type 2 diabetes
Discover twiist- Lum JW, et al. A Real-World Prospective Study of the Safety and Effectiveness of the Loop Open Source Automated Insulin Delivery System. Diabetes Technol Ther. 2021;23(5):367-375.
- Wong JJ, et al. Psychosocial Effects of the Loop Open-Source Automated Insulin Delivery System. J Diabetes Sci Technol. 2023;17(6):1440-1447.

